C11orf65,11号染色体开放阅读框65抗体

产品编号HZ-9940R
英文名称C11orf65
中文名称11号染色体开放阅读框65抗体
别 名Chromosome 11 open reading frame 65; Hypothetical protein LOC160140; CK065_HUMAN.
说 明 书0.1ml 0.2ml
研究领域细胞生物 免疫学 细胞周期蛋白
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Cow, Horse, Rabbit, Sheep,
C11orf65,11号染色体开放阅读框65抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量37kDa
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human C11orf65
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
C11orf65,11号染色体开放阅读框65抗体PubMedPubMed
产品介绍background:
C11orf65, also known as MGC33948, is a 313 amino acid protein that is encoded by a gene located on human chromosome 11. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and β thalassemia are caused by HBB gene mutations. Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.

Post-translational modifications:

Database links:
Entrez Gene: 160140 Human
SwissProt: Q8NCR3 Human
SwissProt: Q9D4W2 Mouse
SwissProt: Q569B9 Rat

C11orf65,11号染色体开放阅读框65抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.