分子量：Calculated MW: 41kDa
Observed MW: 41kDa

细胞定位：Cell membrane, Multi-pass membrane protein

稀释方法：WB 1:500 - 1:2000
IF 1:50 - 1:200

总结：This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene.