肺癌基因表达PCR芯片
产品名称: 肺癌基因表达PCR芯片
英文名称: Lung Cancer PCR Array
产品编号:
产品价格: 4000
产品产地: null
品牌商标: null
更新时间: null
使用范围: null
上海杏园生物科技有限公司
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肺癌基因表达PCR芯片可用于研究与肺癌发展相关的的84个关键基因的表达。该芯片包含肺癌样品中常规检测的基因,启动子发生甲基化变化的基因以及和肿瘤转移相关的基因。利用该芯片,研究者可以方便并且可信地对与肺癌发生发展以及转移相关的基因进行同时检测。Differentially Methylated Promoters: APBA1, APC, CADM1, CDH1, CDH13,CDKN1C, CDKN2A, CDKN2B, CXCL12, CYP1B1, DLC1, FHIT, MGMT, MLH1, MTHFR,OPCML, PRDM2, RASSF1, RASSF2, SFRP1, TCF21. Metastatic Potential:ANXA5, DUSP6, ERBB3, HGF, HMMR, IRF4, LCK, MET, MMD, NF1, STAT1, STAT2.Differentially Expressed Genes in Adenocarcinoma (AC) Versus SquamousCell Carcinoma (SCC): Higher in AC than in SCC: CLCA2, DSG3, KRT5,KRT14, SPRR1A. Higher in SCC than in AC: AGR2, LGSN, NKX2-1, SFTA3,SPINK1. Up-Regulated in Lung Cancer: CEACAM5, COL11A1, CP, CXCL13,GREM1, MKI67, MMP1, MMP12, SPINK1, SPP1, TOP2A, TOX3. Down-Regulated inLung Cancer: AGER, CA4, CLDN18, CLIC5, FABP4, GPM6A, SCGB1A1, SFTPC,SOSTDC1, WIF1. PI3K/AKT Signaling: AKT1, BCL2, CDH1, CDKN2A, EGFR,NFKB1, TP53, VEGFA. Apoptosis: ANXA5, APC, BCL2, BIRC5, BRAF, CADM1,CDH1, CDH13, CDKN2A, DLC1, EGFR, ERBB2, ERBB3, HGF, HRAS, KRAS, LCK,MLH1, MMP9, NF1, NFKB1, PTGS2, SFRP1, STAT1, TERT, TGFB1, TNF, TOP2A,TP53, VEGFA. Cell Cycle Regulation: APC, BCL2, BIRC5, CDKN1C, CDKN2A,CDKN2B, EGFR, PTGS2, RB1, TGFB1, TNF, TP53. Immune Response: BCL2,CADM1, CSF3, CXCL12, CXCL13, IRF4, LCK, MLH1, MMD, NFKB1, PAX5, STAT1,STAT2, TGFB1, TNF, TP53, VEGFA. Extracellular Matrix & CellAdhesion: CADM1, CDH1, CDH13, CEACAM6, CLDN18, COL11A1, DSG3, GPM6A,HMMR, KRT14, KRT5, MET, MMP1, MMP12, MMP9, SFTA3, SFTPC.
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