SOX13,核转录因子SOX13抗体

产品编号HZ-11586R
英文名称SOX13
中文名称胰岛细胞抗原12/核转录因子SOX13抗体
别 名ICA 12; ICA12; Islet cell antibody 12; Islet cell antigen 12; MGC117216; SOX 13; SOX 13 protein; sox13; SOX13 protein; SOX13_HUMAN; SRY (Sex determining region Y)-box 13; SRY box 13; SRY box containing gene 13; SRY related HMG box gene 13; SRY sex determining region Y box 13; Transcription factor SOX 13; Transcription factor Sox-13; Type 1 diabetes autoantigen; Type 1 diabetes autoantigen ICA 12; Type 1 diabetes autoantigen ICA12.
说 明 书0.1ml 0.2ml
研究领域信号转导 转录调节因子 表观遗传学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Horse,
SOX13,核转录因子SOX13抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量69kDa
细胞定位细胞核
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human ICA12 (401-500aa)
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
SOX13,核转录因子SOX13抗体PubMedPubMed
产品介绍background:
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. It has also been determined to be a type-1 diabetes autoantigen, also known as islet cell antibody 12. [provided by RefSeq, Jul 2008]

Function:
Binds to the sequence 5'-AACAAT-3'.

Subcellular Location:
Nucleus.

Tissue Specificity:
Highly expressed in kidney, lung, and liver and low expression in thymus, brain, spleen, and muscle.

Similarity:
Contains 1 HMG box DNA-binding domain.

Database links:
Entrez Gene: 9580 Human
Entrez Gene: 20668 Mouse
Entrez Gene: 289026 Rat
Omim: 604748 Human
SwissProt: Q9UN79 Human
SwissProt: Q04891 Mouse
Unigene: 201671 Human
Unigene: 8575 Mouse

SOX13,核转录因子SOX13抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.