IL-27 (human):Fc (human) (rec.) (non-lytic)-蛋白质/抗原/多肽-试剂-生物在线
江苏泰利达生物科技有限公司
IL-27 (human):Fc (human) (rec.) (non-lytic)

IL-27 (human):Fc (human) (rec.) (non-lytic)

商家询价

产品名称: IL-27 (human):Fc (human) (rec.) (non-lytic)

英文名称:

产品编号: CHI-HF-22027

产品价格: 0

产品产地: USA

品牌商标: chimerigen

更新时间: null

使用范围: null

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Synonyms :    Interleukin-27
Host :  CHO cell
Sequence :  The human IL-27 complex composed of the Ebi3 subunit(NP_005746.2)(Arg21-Lys229) and the p28 subunit(NP_663634.2)(Val26-Pro243) is fused through a polypeptide linker to the Fc portion of a mutant human IgG1.
Molecular Mass:  78 KDa (monomer)
Non-lytic:  Acts as a long lasting fusion protein which only binds to the receptor. Mutations to the complement(C1q) and FcgRI  binding sites of the IgGs Fc fragment render the fusion proteins incapable of antibody directed cytotoxicity(ADCC) and complement directed cytotoxicity (CDC).
Purity :  >98%,by SDS-PAGE under reducing conditions. 
Endotoxin Content :  <0.06 EU/μg as determined by LAL test.

Activity :  Bioactivity was measured in a cell proliferation assay using anti-CD3 activated human peripheral mononuclear cells.
Formulation :  Lyophilized from 0.2μm-filtered solution in PBS.
Reconstitution :  Reconstitute at 100μg/ml in sterile PBS.
Use / Stability :
Stable for at least 1 year after receipt when stored at -20℃. Working aliquots are stable for up to 3 months when stored at -20℃.
Avoid freeze/thaw cycles.