FITC标记的硫辛酰连接酶抗体
产品名称： FITC标记的硫辛酰连接酶抗体
英文名称： Anti-LIPT1/FITC
产品编号： HZ-18298R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-LIPT1/FITC Conjugated antibody
FITC标记的硫辛酰连接酶抗体
| 英文名称 | Anti-LIPT1/FITC |
| 中文名称 | FITC标记的硫辛酰连接酶抗体 |
| 别 名 | Lipoate biosynthesis protein; Lipoate-protein ligase; Lipoyl ligase; Lipoyltransferase 1; Lipoyltransferase 1 mitochondrial; LIPT_HUMAN; Lipt1; mitochondrial. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 信号转导 转录调节因子 新陈代谢 线粒体 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 41kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human LIPT1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The process of transferring lipoic acid to proteins is a two-step process. The first step is the activation of lipoic acid by lipoate-activating enzyme to form lipoyl-AMP. For the second step, the protein encoded by this gene transfers the lipoyl moiety to apoproteins. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 13. Read-through transcription also exists between this gene and the neighboring downstream mitochondrial ribosomal protein L30 (MRPL30) gene. [provided by RefSeq, Mar 2011] Function: Catalyzes the transfer of the lipoyl group from lipoyl-AMP to the specific lysine residue of lipoyl domains of lipoate-dependent enzymes. Subcellular Location: Mitochondrion. Tissue Specificity: Highly expressed in skeletal muscle and heart, moderately in kidney and pancreas, and detected at lower levels in liver, brain, placenta and lung. Similarity: Belongs to the lplA family. Database links: Entrez Gene: 51601 Human Omim: 610284 Human SwissProt: Q9Y234 Human Unigene: 719172 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
硫辛酸转移到蛋白质的过程是一个两步过程。第一步是用脂酸激活酶激活硫辛酸形成脂酰AMP。第二步，由该基因编码的蛋白质将脂酰基部分转移到载脂蛋白。选择性剪接导致多个转录变体。在第13号染色体上已鉴定出一个相关的假基因。该基因与相邻的下游线粒体核糖体蛋白L30（MRPL30）基因之间也存在读出转录。〔RefSeq，2011〕