产品简介
英文名称
Anti-ARRB1 Polyclonal Antibody
宿主
Rabbit
别名
ARB1;ARR1;ARRB1;ARRB1_HUMAN;Arrestin 2;Arrestin beta 1;Arrestin beta-1;Beta-arrestin-1;
稀释比例
IHC 1:25-100.
蛋白分子量
46/47kDa
Gene ID
408
保存
Store at -20°C. Avoid freeze / thaw cycles.
储存液
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法
Affinity purification
亚型
IgG
免疫原
A synthetic peptide of Human ARRB1
亚细胞定位
Nucleus Cytoplasm
Swiss Prot
P49407
背景资料
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described.
Public Immunogen Range
325-375/418aa
克隆类型
Polyclonal Antibody
交叉反应
Human Rat Mouse
应用
IHC
规格
50ul 100ul
备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
实验图
Immunohistochemistry of paraffin-embedded Human colorectal cancer with ARRB1 antibody diluted at