ZDHHC-12,锌指蛋白Zdhhc12抗体

产品编号HZ-6958R
英文名称ZDHHC-12
中文名称锌指蛋白Zdhhc12抗体
别 名DHHC12; DHHC-12; Palmitoyltransferase ZDHHC12; ZDH12_HUMAN; Zdhhc12; Zinc finger DHHC domain-containing protein 12; DHHC-12; Probable palmitoyltransferase ZDHHC12; ZDH12_HUMAN; ZDHHC12; Zinc finger DHHC domain-containing protein 12; Zinc finger DHHC type containing 12; Zinc finger protein 400; ZNF400.
说 明 书0.1ml 0.2ml
研究领域细胞生物 信号转导 转录调节因子 锌指蛋白
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse,
ZDHHC-12,锌指蛋白Zdhhc12抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量30kDa
细胞定位细胞膜
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human ZDHHC-12
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
ZDHHC-12,锌指蛋白Zdhhc12抗体PubMedPubMed
产品介绍background:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZDHHC12 (zinc finger, DHHC domain containing 12), also known as ZNF400, is a 267 amino acid multi-pass membrane protein that contains one DHHC-type zinc finger and is thought to function as a palmitoyltransferase, catalyzing the transformation of palmitoyl-CoA and a cysteine-conjugated protein to a S-palmitoyl protein and free CoA. Three isoforms exist due to alternative splicing events. The gene encoding ZDHHC12 maps to human chromosome 9, which consists of about 145 million bases and 4% of the human genome and encodes nearly 900 genes. Chromosome 9 is considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype.

Subcellular Location:
Membrane; Multi-pass membrane protein

Similarity:
Belongs to the DHHC palmitoyltransferase family.
Contains 1 DHHC-type zinc finger.

Database links:
Entrez Gene: 505354 Cow
Entrez Gene: 608478 Dog
Entrez Gene: 100066906 Horse
Entrez Gene: 84885 Human
Entrez Gene: 100519816 Pig
Entrez Gene: 366014 Rat
SwissProt: Q96GR4 Human
SwissProt: Q6DGF5 Rat
Unigene: 133122 Human
Unigene: 95138 Rat

ZDHHC-12,锌指蛋白Zdhhc12抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.