人活性ATAD2蛋白片段 核信号转导-蛋白质/抗原/多肽-试剂-生物在线
深圳市宇德立生物科技有限公司
人活性ATAD2蛋白片段 核信号转导

人活性ATAD2蛋白片段 核信号转导

商家询价

产品名称： 人活性ATAD2蛋白片段 核信号转导

英文名称： AAA nuclear coregulator cancer-associated protein AAA nuclear coregulator, cancer-associated ANCCA Atad2 ATAD2_HUMAN ATPase family AAA domai

产品编号： ab198131

产品价格： 0

产品产地： 英国

品牌商标： abcam

更新时间： null

使用范围： null

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进入展台

 

  • 性质Recombinant
  • 来源E. coli
  • 氨基酸序列
    • AccessionQ6PL18
    • 种属Human
    • 序列MSPILGYWKIKGLVQPTRLLLEYLEEKYEEHLYERDEGDKWRNKKFELGL EFPNLPYYIDGDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVL DIRYGVSRIAYSKDFETLKVDFLSKLPEMLKMFEDRLCHKTYLNGDHVTH PDFMLYDALDVVLYMDPMCLDAFPKLVCFKKRIEAIPQIDKYLKSSKYIA WPLQGWQATFGGGDHPPKSDLEVLFQGPLGSQEEDTFRELRIFLRNVTHR LAIDKRFRVFTKPVDPDEVPDYVTVIKQPMDLSSVISKIDLHKYLTVKDY LRDIDLICSNALEYNPDRDPGDRLIRHRACALRDTAYAIIKEELDEDFEQ LCEEIQESR
    • 分子量42 kDa including tags
    • 氨基酸981 to 1108
    • 标签GST tag N-Terminus
    • 额外的序列信息Bromodomain; NM_014109.

技术指标

Our Abpromise guarantee covers the use of ab198131 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性

    Assay was performed using an ATAD2 Inhibitor Screening Assay Kit.

  • 应用

    Functional Studies

    SDS-PAGE

  • 纯度>= 95 % by SDS-PAGE.

  • 形式Liquid
  • 浓度100 µg 浓度为 2.67 mg/ml 

制备和贮存

  • 稳定性和存储

    Shipped on Dry Ice. Store at -80°C. Avoid freeze / thaw cycle.

    pH: 8
    Constituents: 0.71% Tris HCl, 0.72% Sodium chloride, 0.02% Potassium chloride, 10% Glycerol

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

常规信息

  • 别名
    • AAA nuclear coregulator cancer-associated protein
    • AAA nuclear coregulator, cancer-associated
    • ANCCA
    see all
  • 功能May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells.
  • 组织特异性Highly expressed in estrogen receptor positive breast tumors and in osteosarcoma tumors.
  • 序列相似性Belongs to the AAA ATPase family.
    Contains 1 bromo domain.
  • 细胞定位Nucleus.
  • Information by UniProt

Active human ATAD2 protein fragment 图像

  • Functional Studies - Active human ATAD2 protein fragment (ab198131)
    Functional Studies - Active human ATAD2 protein fragment (ab198131)

    Activity assay using ab198131.

  • SDS-PAGE - Active human ATAD2 protein fragment (ab198131)
    SDS-PAGE - Active human ATAD2 protein fragment (ab198131)