IgG4抗原

其它名称：免疫球蛋白IgG4蛋白，IgG4 protein，IgG4蛋白

货号：G7043

应用：Standard

特异性：Human IgG4

来源：重组蛋白

存贮：-20℃

免疫球蛋白IgG，由B淋巴细胞激活的浆细胞分泌产生。是人血清中最丰富的蛋白质之一。IgG又分为四种亚型（IgG1,IgG2，IgG3，IgG4）,最主要的是IgG1,而IgG4占总IgG的5%左右。

产品说明

IgG1 immunoglobulin is most prevalent (>50%) and the IgG4 variety constitutes less than 5%. IgG4 has disulfide bonds linking the heavy chains unsteadily, allowing their separation and forming 2 antigen-binding sites, so that the bispecific antibody is asymmetric with an unclear in vivo role. IgG4 interacts with the Fc portion of IgG1–3 and not through the Fab-Fc, as occurs with other immunoglobulins, and has rheumatoid factor activity. Therefore, IgG4 has little or no cross-reactivity between antigens and rarely forms immune complexes having no complement activation capacity

This product is for research use only. It is not intended for diagnostic or therapeutic use.

注意事项：

1.本品为蛋白质制剂，未添加任何防腐剂和保护剂，在2-8℃可短期保存

2.本品作为诊断试剂原辅材料，不得直接用于诊断或治疗。