NAT8 + NAT8B,N-乙酰转移酶8抗体

产品编号HZ-11591R
英文名称NAT8 + NAT8B
中文名称N-乙酰转移酶8抗体
别 名NAT8+NAT8B; Camello-like protein 1; NAT8; NAT8_HUMAN; Probable N-acetyltransferase 8; Camello like protein 2; Camello-like protein 2; CML2; Hcml2; N acetyltransferase 8B; NAT8B; NAT8B_HUMAN; NAT8BP; Probable N acetyltransferase 8B; Probable N-acetyltransferase 8B.
说 明 书0.1ml 0.2ml
研究领域肿瘤 细胞生物 发育生物学 信号转导 细胞周期蛋白
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Horse,
NAT8 + NAT8B,N-乙酰转移酶8抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:20-200 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量26kDa
细胞定位细胞膜
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human NAT8 (141-220aa)
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.
NAT8 + NAT8B,N-乙酰转移酶8抗体PubMedPubMed
产品介绍background:
NAT8 gene, isolated using the differential display method to detect tissue-specific genes, is specifically expressed in kidney and liver. The encoded protein shows amino acid sequence similarity to N-acetyltransferases. A similar protein in Xenopus affects cell adhesion and gastrulation movements, and may be localized in the secretory pathway. A highly similar paralog is found in a cluster with this gene. [provided by RefSeq, Sep 2008].
NAT8B protein encoded by this gene is highly similar to the N-acetyltransferase 8 (NAT8) gene product, which is a kidney and liver protein with homology to bacterial acetyltransferases involved in drug resistance. This gene is localized on chromosome 2 in the vicinity of the NAT8 gene and may represent a pseudogene of NAT8. This gene contains two polymorphic nonsense mutations that disrupt the active site of the protein. The full-length product of this gene contains a complete acetyltransferase domain and is identical in length to NAT8. [provided by RefSeq, Jul 2008].

Function:
Plays a role in regulation of gastrulation.

Subcellular Location:
Membrane.

Tissue Specificity:
Expression is restricted to liver and kidney.

Similarity:
Belongs to the camello family.
Contains 1 N-acetyltransferase domain.

NAT8 + NAT8B,N-乙酰转移酶8抗体Database links:
Entrez Gene: 9027 Human
Entrez Gene: 51471 Human
NCBI: NP_057431 Human
Omim: 606716 Human
Omim: 608190 Human
SwissProt: Q9UHE5 Human
SwissProt: Q9UHF3 Human
Unigene: 14637 Human
Unigene: 728429 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.